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Novartis Spins Off Sandoz: What the $10B Pure-Play Means for Biosimilar Strategies and Drug Pricing 2025-2026
Deals
With Sandoz now independent and over $10B in revenue, the generics giant faces a high-stakes biosimilars battl…
Apr 7, 2026
Amgen’s $27.8B Horizon Buy: Betting Big on Rare Diseases, Revenue Multiples, and Pipeline Synergies
Deals
Amgen’s $27.8B bet on Horizon Therapeutics puts rare disease revenue and high-margin growth at center stage -b…
Feb 27, 2026
The Economics of Pharma Mega-Mergers: Why Most Buyers Overpay
Deals
AbbVie’s Allergan deal touted $2B in annual savings, but mega-merger math rarely favors acquirers. A close loo…
Jan 19, 2026
Negotiations
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Aetna’s 2026 Step Therapy Expansion: Biologic Manufacturers Face $7B Battleground
Negotiations
By shifting step therapy policy on high-cost biologics, Aetna has upended specialty drug contracting -and set …
Mar 26, 2026
Patient Access and Insurer Costs: The Ongoing Battle Over Copay Accumulator Programs in 2025
Negotiations
Nearly $19B in annual copay assistance is up for grabs as insurers and drugmakers escalate their fight over ac…
Mar 3, 2026
How PBM Rebate Negotiations Actually Work: The Formulary Placement Auction That Sets Patient Costs
Negotiations
Behind closed doors, PBM rebate talks resemble a competitive auction, deciding which drugs make the formulary …
Jan 30, 2026
State PBM Legislation 2025-2026: National Chains Absorb, Independents Scramble
Policy
State PBM rules in 2025-2026 mean new six-figure legal and data costs for independents, while chains like CVS …
Mar 21, 2026
IRA Price Negotiation Year One: What the Numbers Reveal About CMS, Drugmakers, and the Real Deals
Policy
In its inaugural round, CMS demanded deep price cuts on blockbuster drugs under the IRA. Drugmakers pushed bac…
Feb 5, 2026
IRA Price Negotiation Year One: Who Blinked, Who Balked, and What's Next for Big Ticket Drugs
Policy
First-round IRA negotiations saw average price cut offers near 29 percent, but some manufacturers accepted con…
Jan 22, 2026
CRISPR Therapeutics’ CS37 in Hemophilia B: Breakthrough Candidate or Regulatory Gamble?
Pipeline
CS37’s single-dose gene editing could upend hemophilia B economics, but regulators and payers are watching lon…
Mar 24, 2026
Late-Stage Obesity Drugs Beyond GLP-1s: Orforglipron, Survodutide, and the Oral Alternatives That Could Reshape Pricing
Pipeline
As orforglipron and survodutide close in on approval, pharma faces a new pricing puzzle in the $80B obesity ma…
Feb 18, 2026
Obesity Pipeline Beyond GLP‑1s: Orforglipron, Survodutide, and the Oral Disruptors
Pipeline
Lilly’s oral orforglipron and Boehringer’s survodutide aren’t just chasing Wegovy. Their late-stage data and p…
Jan 27, 2026
Spinraza’s 2025 Cliff: Biogen, Patent Expiry, and the New Pricing Squeeze
Money
Spinraza’s US patent expires in 2025, with nearly $2B at risk. Biogen faces real revenue compression as payers…
Apr 4, 2026
Lilly’s Mounjaro Pricing Strategy: Gross-to-Net Math Behind Market Dominance
Money
Lilly’s $1,023 list for Mounjaro signals a familiar but risky gross-to-net playbook in the GLP-1 market. The s…
Mar 6, 2026
Gross-to-Net Dynamics in Pharma Earnings: Decoding the Real Revenue Numbers
Money
Gross-to-net deductions swallow half the list price for many drugs, distorting both earnings and drug pricing …
Feb 13, 2026
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